Prozac has brand recognition, having permeated our culture as few medications
have before. We live in the Age of Prozac.
In the 1993 bestseller Listening to Prozac,1 Kramer meditated on “cosmetic psychopharmacology”:
fluoxetine targeting not only depressive episodes but, seemingly, patients’
personalities. Responders often felt “better than well.” This
book’s authors generally interpret this as personality change, but it
usually indicates lifting of depression so chronic that patients themselves
consider it their personality.2 The phenomenon
largely reflects selective serotonin reuptake inhibitor (SSRI) effects on
dysthymic patients without prior adequate treatment for chronic depression
and anxiety. Treating superimposed major depression clears both acute depression
and dysthymic disorder, granting newfound euthymia.
Markowitz JC. Prozac. JAMA. 2005;293(2):237–238. doi:10.1001/jama.293.2.237
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