A new antibiotic shows promise for treating tuberculosis (TB) more swiftly
than current anti-TB drugs, according to research by scientists in Belgium,
France, Sweden, and the United States. The study was published on December
9 in an online edition of Science (http://www.sciencemag.org).
The drug, called R207910, belongs to a newly discovered family of compounds
called diarylquinolines and appears to have a mechanism of action that differs
from that of other antibiotics used to treat TB or other infections, impeding
the cell’s ability to produce energy in the form of adenosine triphosphate.
Cell culture studies found that R207910 potently inhibits both drug-sensitive
and drug-resistant TB bacteria, the researchers reported.
Stephenson J. New Antibiotic for TB?. JAMA. 2005;293(3):286. doi:10.1001/jama.293.3.286-a