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February 2, 2005

Comparison of MRI and CT for Detection of Acute Intracerebral Hemorrhage—Reply

JAMA. 2005;293(5):550-551. doi:10.1001/jama.293.5.550-b

In Reply: Dr Eliasziw and Ms Paddock-Eliasziw suggest that a κ statistic rather than a McNemar test for proportions could have been used to summarize the results of our study. We chose to use the McNemar test because our primary goal was to show the equivalence of MRI for detecting hemorrhage compared to CT. Had we used the κ statistic, a point estimate of 0.84 would still suggest a strong correlation. Perhaps more important than the choice of statistical approach are the actual data. Acute hemorrhage was missed in 4 cases with each modality. With MRI, the hemorrhages were interpreted as chronic rather than acute in 3 patients. With CT, the hemorrhages were completely missed.