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Books, Journals, New Media
February 9, 2005


JAMA. 2005;293(6):743-747. doi:10.1001/jama.293.6.743-b

Five years have passed since publication of the previous edition of this classic text, and, as expected, numerous changes, in both format and emphasis on disease mechanisms, are readily identified. In this multiauthored text (25 contributors and three editors), pathologic and pathophysiologic processes are demonstrated with a blending of textual material, gross and microscopic photographs, line drawings and illustrations, flow charts, and tables. (Some of the diagrams are so beautifully constructed that one can gain an understanding of the essential mechanism involved just by studying them without reference to the text.) The first third of the book is devoted to the basic disease mechanisms—inflammation and infection, nutritional disorders, neoplasia, genetics, cell injury and death, hemodynamic disorders—while the remaining text applies these fundamental principles to the specific organs and organ systems.