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May 4, 2005

Use of Niacin During Non–ST-Segment Elevation Acute Coronary Syndromes—Reply

JAMA. 2005;293(17):2092-2093. doi:10.1001/jama.293.17.2093

In Reply: Dr Goldstein raises concern over the use of nicotinic acid (niacin) in the acute management of patients with non–ST-segment elevation acute coronary syndromes. This is based on a case report from 1991 that describes worsened ischemia in 2 patients with unstable angina following the administration of crystalline niacin.1 We are aware of no other similar reports.

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