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May 11, 2005

Consumption of Vegetables and Fruits and Risk of Breast Cancer

JAMA. 2005;293(18):2209-2210. doi:10.1001/jama.293.18.2209-a

To the Editor: In the European Prospective Investigation Into Cancer and Nutrition (EPIC) cohort study, Dr van Gils and colleagues found no association between the consumption of fruits or vegetables and breast cancer risk.1 The authors note that their results are compatible with those from a pooled analysis of cohort studies2 and argue that the findings from case-control studies pointing to a protective effect of intake of fruits and vegetables against breast cancer3 are likely to be due to recall bias or selection bias. Although this is possible, alternative explanations need to be considered before the findings from case-control studies are discounted.

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