To the Editor: In the European Prospective
Investigation Into Cancer and Nutrition (EPIC) cohort study, Dr van Gils and
colleagues found no association between the consumption of fruits or vegetables
and breast cancer risk.1 The authors note that
their results are compatible with those from a pooled analysis of cohort studies2 and argue that the findings from case-control studies
pointing to a protective effect of intake of fruits and vegetables against
breast cancer3 are likely to be due to recall
bias or selection bias. Although this is possible, alternative explanations
need to be considered before the findings from case-control studies are discounted.
Lagiou P, Olsen J, Trichopoulos D. Consumption of Vegetables and Fruits and Risk of Breast Cancer. JAMA. 2005;293(18):2209–2210. doi:10.1001/jama.293.18.2209-a
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