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May 25, 2005

Angina With “Normal” Coronary Arteries

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;293(20):2468-2469. doi:10.1001/jama.293.20.2468-b

To the Editor: In their Clinical Review of angina with normal coronary arteries,1 Drs Bugiardini and Bairey Merz discussed patients admitted to emergency departments complaining of chest pain without significant coronary heart disease (CHD) that could justify their clinical symptoms. In considering women with positive myocardial perfusion scans and electrocardiographic changes but normal coronary arteries, they emphasize that endothelial function may play a key role in the pathophysiology.