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July 13, 2005

Prone Positioning in Children With ARDSPositive Reflections on a Negative Clinical Trial

Author Affiliations

Author Affiliations: Departments of Critical Care Medicine, Anesthesia, and Physiology, Hospital for Sick Children, University of Toronto, Ontario.

JAMA. 2005;294(2):248-250. doi:10.1001/jama.294.2.248

Acute respiratory distress syndrome (ARDS) is common, highly lethal, and not curable. Although important adult ARDS studies1,2 continue to undergo reappraisal,3,4 promising data have recently been reported for treatment of this entity in children. A recent randomized controlled trial,5 which described a beneficial effect of surfactant, was the first report of an effective treatment for ARDS.

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