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October 5, 2005

Nonoccupational HIV Postexposure Prophylaxis

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2005;294(13):1615-1616. doi:10.1001/jama.294.13.1615-a

To the Editor: We agree with the perspective of Drs Merchant and Mayer in their Commentary1 that the new Centers for Disease Control and Prevention (CDC) guidelines for provision of human immunodeficiency virus (HIV) nonoccupational postexposure prophylaxis (HIV NPEP)2 represents an important initial step in advising clinicians. However, we note an important caveat with regard to the choice of antiretroviral agents, as discussed in the clinical guidelines developed by the New York State Department of Health AIDS Institute (NYSDOH AI) in 1997 and updated in December 2004.3,4