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November 2, 2005

Fish Oil Supplementation and Arrhythmias

JAMA. 2005;294(17):2165-2166. doi:10.1001/jama.294.17.2165-a

To the Editor: Dr Raitt and colleagues1 conclude that “fish oil supplementation in patients with ICDs [implantable cardioverter-defibrillators] and recurrent ventricular arrhythmias should be avoided” and that its use “may be proarrhythmic in some patients.” We think that the study findings must be placed into context. Although there was a shortened time to recurrent ventricular tachycardia (VT) with fish oil, there was no increase in mortality or incidence of ventricular fibrillation (VF) nor any effect on defibrillation threshold or the inducibility of VT/VF.

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