In Reply: Dr Gnecchi-Ruscone raises the question of whether the previously reported predominance of Takotsubo cardiomyopathy in women is preserved in a setting of a large catastrophic event such as an earthquake. Among the 25 patients we described with Takotsubo cardiomyopathy following the Niigata-Chuetsu earthquakes in 2004, 24 (96%) were women. The mean age was 71.0 years (range, 49-83 years). Of the 2 patients with Takotsubo cardiomyopathy during the 20 control weeks, one was a woman and one was a man.
Watanabe H, Kodama M, Aizawa Y, Tanabe N. Earthquakes and Takotsubo Cardiomyopathy—Reply. JAMA. 2005;294(17):2169–2170. doi:10.1001/jama.294.17.2169-c
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