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Editorial
January 25, 2006

Theme Issue on Men's HealthCall for Papers

JAMA. 2006;295(4):440-441. doi:10.1001/jama.295.4.440

Gender-based medicine—specifically recognizing and understanding differences in the health of men and women—drew much attention in the 1990s. The National Institutes of Health's Office of Research on Women's Health was established in 1990.1 The inclusion of women (and minorities) in clinical trials in sufficient number to allow analysis of differences in intervention effect became public law when Congress made this provision part of the NIH Revitalization Act of 1993 (Pub L No. 103-43).2 With seemingly similar purpose, the US Food and Drug Administration (FDA) issued a guideline in 19933 that emphasized the importance of including both men and women in clinical trials evaluating new medications, and in 1994 the FDA created an Office of Women's Health.4 Over the past decade, there has been a dramatic increase in the quantity and quality of research devoted to examining numerous aspects of women's health such that today, women's health research is most definitely mainstream.5

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