To the Editor: Dr Belda and colleagues1 found that patients receiving supplemental inspired oxygen at a fraction of inspired oxygen (FIO2) of 80% had a reduced risk of surgical wound infection compared with those who received oxygen at FIO2 of 30%. I have concerns regarding the method of oxygen administration that was used in these patients.
Agarwal R. Supplemental Oxygen and Risk of Surgical Wound Infection. JAMA. 2006;295(14):1641–1643. doi:10.1001/jama.295.14.1641-a
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