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The World in Medicine
April 19, 2006

Gene Linked to Skin Disorder

JAMA. 2006;295(15):1763. doi:10.1001/jama.295.15.1763-a

New research indicates that the risk of developing atopic dermatitis is increased by mutations that undermine the function of filaggrin, a skin component that helps block the entry of disease agents such as toxins and allergens. The findings, by an international team of scientists, were published in an advanced online edition of Nature Genetics (Palmer CNA et al. http://dx.doi.org/10.1038/ng1767 [published online ahead of print March 19, 2006]).