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Medical News & Perspectives
October 11, 2006

Genetic Link Found for Premature Birth Risk

JAMA. 2006;296(14):1713-1716. doi:10.1001/jama.296.14.1713

Researchers have identified a genetic variant in black women that increases the risk of preterm premature rupture of membranes (PPROM)—a leading cause of preterm birth (Wang H et al. Proc Natl Acad Sci U S A. doi: 10.1073/pnas. 0603676103 [published online ahead of print August 21, 2006]).

“This is probably the most convincing study to date that specific, fairly common, genetic variants will increase risk,” said Nancy Green, MD, medical director of the March of Dimes.