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October 25, 2006

Funding of Clinical Trials

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2006;296(16):1969. doi:10.1001/jama.296.16.1969-a

To the Editor: In their study of reported outcomes in major cardiovascular trials, Dr Ridker and Mr Torres1 found that clinical trials funded by for-profit organizations were more likely to report positive findings than those funded by not-for-profit organizations, which were more likely to report results that were negative. One explanation not considered in their discussion is the possibility that the private sector is better able to predict a positive outcome.

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