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November 22/29, 2006

Fluoxetine for Treatment of Anorexia Nervosa—Reply

JAMA. 2006;296(20):2439-2440. doi:10.1001/jama.296.20.2440

In Reply: Dr Dettling and colleagues request information about psychiatric comorbidity in the study participants. Diagnoses based on structured interviews were available for 92 of the 93 patients. At the time of randomization, 11 (12.0%) met criteria for a major depressive disorder and 12 (13.0%) met criteria for obsessive-compulsive disorder. These numbers were too small to permit any meaningful statistical analysis and, therefore, were not reported in the article. We concur with the need for additional studies of other pharmacological agents for patients with this challenging illness.