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Commentary
January 24/31, 2007

Practice-Based Research—“Blue Highways” on the NIH Roadmap

JAMA. 2007;297(4):403-406. doi:10.1001/jama.297.4.403

On the old highway maps of America, the main routes were red and the back roads blue. Now even the colors are changing. But in those brevities just before dawn and a little after dusk—times neither day nor night—the old roads return to the sky some of its color. Then, in truth, they carry a mysterious cast of blue, and it's that time when the pull of the blue highway is strongest, when the open road is a beckoning, a strangeness, a place where a man can lose himself.
William Least Heat-Moon, Blue Highways1

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