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Book and Media Reviews
February 21, 2007

The MD Anderson Manual of Medical Oncology

Author Affiliations

Book and Media Reviews Section Editor: John L. Zeller, MD, PhD, Fishbein Fellow, JAMA.

JAMA. 2007;297(7):748-752. doi:10.1001/jama.297.7.748

Medical oncology is a rapidly changing subspecialty. Clinical trial results and new therapies change approaches to treatment literally overnight. Therapy with broadly toxic agents has evolved into targeted genetic and enzymatic approaches to destroying or controlling cancer cells. Surgical tumor removal has become more effective. Radiation has become more precise in targeting both static and dynamic tumor locations. Medical imaging has improved, with the development of stronger magnets for magnetic resonance imaging and enhanced-resolution positron emission tomography to spot malignancies that would be undetectable with computed tomography. However, limitations of diagnosis and therapy continue to be major barriers to cure.