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March 7, 2007

Advanced Prostate Cancer and Postoperative Radiotherapy

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2007;297(9):950-951. doi:10.1001/jama.297.9.950-a

To the Editor: In their study of the effect of adjuvant postoperative radiotherapy on the clinical outcome for men with stage T3 prostate cancers, Dr Thompson and colleagues1 demonstrated that external beam radiation therapy in the range of 60 to 64 Gy resulted in a statistically significant reduction in the risk of prostate-specific antigen relapse and disease recurrence, while improvement in disease-free-survival was close to statistical significance. Overall survival did not appear to be affected by postoperative radiation therapy.