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March 14, 2007

Chlorhexidine Gluconate for Prevention of Nosocomial Infection in Cardiac Surgery

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2007;297(10):1059-1060. doi:10.1001/jama.297.10.1059-b

To the Editor: Dr Segers and colleagues1 presented a randomized controlled trial that studied the prevention of nosocomial infections in patients undergoing cardiac surgery by using chlorhexidine gluconate to decontaminate the nasopharynx and oropharynx. This study was conducted in a community hospital in the Netherlands, and we are concerned that the results may not be generalizable to hospitals in the United States.