Rare diseases have been defined as those with a prevalence of less than 1 per 2000 persons.1 In the case of tumors, an incidence of 3 or fewer per 100 000 persons per year may be considered rare.2
The diagnosis and treatment of rare tumors are challenging to clinical practice. Although effective treatments are available for several rare cancers,3 experience with most is limited, even at outstanding cancer centers, and treatment is commonly based on weak evidence. This situation makes the third edition of Textbook of Uncommon Cancer a must-have reference text. First published in 1988, it provides comprehensive coverage of a broad range of uncommon tumors, from diagnosis to treatment and prognosis.
Rosa DD. Textbook of Uncommon Cancer. JAMA. 2007;297(11):1259–1263. doi:10.1001/jama.297.11.1261-b
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