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Medical News & Perspectives
July 4, 2007

Studies Suggest New Approaches to Pain

JAMA. 2007;298(1):27-28. doi:10.1001/jama.298.1.27

Boston—While physicians may choose among numerous options for treating pain, many conditions would benefit from more effective modalities. Insights from research into the mechanisms of migraine and rare pain disorders are inspiring the search for new analgesics that selectively target pain sources, as researchers discussed at the 59th annual meeting of the American Academy of Neurology here in May.

Migraine mechanics

Over the last 30 years, professor of neurology Michael Moskowitz, MD, and colleagues at Harvard Medical School, in Boston, have been investigating the mechanisms underlying migraine aura and headache. Their work uncovering how an abnormal pattern of brain activity triggers migraine is providing the basis for developing new prophylactic medications for this disorder.