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Health Agencies Update
July 25, 2007

Cancer Trial Axed

JAMA. 2007;298(4):394. doi:10.1001/jama.298.4.394-d

The National Cancer Institute (NCI) has decided to cancel one of the largest US cancer prevention trials ever planned. The STELLAR (Study to Evaluate Letrozole and Raloxifene) trial would have compared the estrogen-blocking drugs letrozole and raloxifene in nearly 13 000 postmenopausal women at high risk for breast cancer.

The trial had been approved by several NCI committees. But in January, NCI Director John Niederhuber called for a new review of the study to examine whether the costly trial would provide sufficiently valuable information to justify its $100 million price tag.

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