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August 15, 2007

Obesity and the Right Brain

Author Affiliations

Letters Section Editor: Robert M. Golub, MD, Senior Editor.

JAMA. 2007;298(7):738-739. doi:10.1001/jama.298.7.738-a

To the Editor: In their Commentary, Drs Alonso-Alonso and Pascual-Leone1 discussed the right brain hypothesis for obesity. We agree that there is a great deal of basic science research needed to understand the complex etiology of obesity and to untangle the biological, cognitive, psychological, and environmental issues that may contribute. However, we feel the authors are premature in linking right prefrontal cortex abnormalities and obesity. There are simpler and more practical reasons for the behaviors observed among obese persons than those the authors cite.