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Comment & Response
January 6, 2015

Reanalyses of Trial Results

Author Affiliations
  • 1Department of Emergency Medicine, University of North Carolina, Chapel Hill
  • 2Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, New Jersey
JAMA. 2015;313(1):92-93. doi:10.1001/jama.2014.15627

To the Editor We agree with Dr Ebrahim and colleagues1 that reanalyses of clinical trial data provide an important opportunity to better understand trial results and that more independent reanalyses are needed. However, the estimate of the number of reanalyses published prior to March 9, 2014, reported by Ebrahim et al1 is incorrect, possibly by a substantial margin.