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July 30, 1910


JAMA. 1910;55(5):388-393. doi:10.1001/jama.1910.04330050026011

HISTORY OF THE SUBJECT  Opportunities to get pure human chyle in quantities sufficient for extensive chemical analysis have been exceedingly rare. In fact, a study of the literature back to the middle of the seventeenth century shows only 126 cases of the appearance of a milky fluid in pleural or peritoneal cavity.These 126 cases fall naturally into two classes: (1) those in which the fluid was chyle, pure or modified, distinguished by the presence of free fat globules, minute in size and tending to rise to the top of the collected fluid as cream rises on milk; (2) those in which the fluid was milky in appearance, and contained fat, not in emulsion, but within fattily degenerated leucocytes and other cellular elements.Senator1 differentiated these two classes and designated them as ascites chylosus and chyliformis respectively. Osler2 in 1900 differentiated a third variety of milky ascites which he called ascites lactescens,

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