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October 8, 1910


JAMA. 1910;55(15):1283. doi:10.1001/jama.1910.04330150043014

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I report this case, first, because of its rare occurrence, as I am unable to find a similar condition reported in literature, and secondly because it emphasizes the importance of laboratory work in cases of obscure diagnosis.

History.—  Miss C. G., unmarried, aged 35, a clerk, entered my service at the Cook County Hospital, June 8, 1910. She had always lived in Chicago and was apparently of good habits. Menstruation began at 14 years, was regular and of the twenty-eight-day type.

Present Illness.—  The patient stated that two weeks before entering the hospital a blister appeared on the lower third of the right leg and that after a few days it opened, and an ulcer followed, for which she sought treatment. She denied having injured the leg or having applied any drug locally. With the exception of the ulcer she said she was in good health.

Past History.—  She was

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