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November 19, 1910

Hexamethylenamin in Pellagra

JAMA. 1910;55(21):1828. doi:10.1001/jama.1910.04330210056020

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To the Editor:—  In The Journal, November 5, p. 1663, Dr. Bagby discusses the hexamethylenamin treatment of pellagra. I have used the same remedy in two cases, giving a dose of 5 grains three times a day. The progress of each patient, while not nearly so remarkable as in Dr. Bagby's case, was very satisfactory. A week ago, however, one of them, who had had an organic heart lesion for years, died suddenly while talking to some friends. This patient had so far recovered as to be able to work half a day at a time. The other patient is improving rapidly. The arsenic treatment has been kept up, and I have been doubtful whether the improvement was due to the hexamethylenamin, the arsenic, or the time of the year, or to these three combined. I began the hexamethylenamin at the suggestion of Dr. Manfred Call of Richmond, who has,

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