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December 3, 1910


JAMA. 1910;55(23):2002. doi:10.1001/jama.1910.04330230060030

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This monograph, which was awarded the 1909 Nathan Lewis Hatfield prize of the College of Physicians of Philadelphia, is a consideration of the subject of edema and certain related topics, on the basis of the author's abundant and original investigations in certain principles of colloid chemistry. It is a wellknown fact that certain colloids possess a great affinity for water, and take it up in large amounts until a condition of saturation is reached. The amount of water which will be taken up varies with the nature of the colloid, and also with the composition of the aqueous solution with which it is in contact; the latter is a very important consideration, as exhibited by such a phenomenon as the great swelling of fibrin when in slightly acidulated solutions. After a study of the influence of various substances dissolved in water on the amount of fluid which various colloids and

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