[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 18.204.55.168. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
December 24, 1910

PREVENTION OF HEMORRHAGE IN PULMONARY TUBERCULOSIS BY THE ADMINISTRATION OF AUTOGENOUS VACCINES

Author Affiliations

Fellow in Pathology, University of Chicago; Bacteriologist, Ottawa Tent Colony OTTAWA, ILL.

JAMA. 1910;55(26):2230-2232. doi:10.1001/jama.1910.04330260038014
Abstract

Discharge of blood from the mouth may be caused by heart disease, carcinoma, hemophilia, arteriosclerosis, vicarious menstruation, hysteria, aneurysm, bleeding gums, or nasal, pharyngeal, or gastric lesion, but the great majority of hemorrhages are from tuberculosis of the lungs.

Stricker1 found 221 of 480 hemorrhages due to tuberculosis, and in 196 more this was probably the cause. Sée1 (1884) says, "Aside from infections diseases, hemophilia, and acute infections of the lungs (pneumonia, abscess, gangrene) we only know of two real causes of hemoptysis—heart disease and pulmonary tuberculosis."

The pathologic conditions preceding hemorrhage vary with the stage of the disease. In early cases it may be due to localized hyperemia in the lung induced by violent or long-continued exercise; or, more likely, due to weakening and erosion of small blood-vessels by the growth of tubercles. Early hemorrhages are always venous; in later stages hemorrhages arise from both the arteries

×