The province of a functional kidney test, in my mind, is not so much to determine the diagnosis in a particular case as it is to prognose the sufficiency of the supposedly healthy twin organ. Often the precise nature of the kidney lesion can be definitely diagnosed without recourse to the estimation of the renal function—witness the skiagram in nephrolithiasis, palpation in conjunction with the other physical and clinical findings in renal tumor, etc. Moreover, it is often absolutely unimportant, from the point of view of treatment, to determine by functional kidney tests the extent of involvement as to sufficiency or non-suffciency of a kidney, the seat of such diseases as calculus, sarcoma, hypernephroma, surgical tuberculosis, etc. The paramount question to be decided is the unilateral or bilateral involvement of the organs and above all the functional integrity of the presumably healthful kidney. It is seldom that the functional test,
THOMAS BA. THE RESULTS OF TWO HUNDRED CHROMO-URETEROSCOPIES EMPLOYING INDIGOCARMIN AS A FUNCTIONAL KIDNEY TEST. JAMA. 1913;60(3):185–188. doi:10.1001/jama.1913.04340030015010
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