Although simple solitary ulcer of the bladder is regarded as a very rare affection, the history of two cases1 that have recently come under my observation would seem to indicate that this condition is not infrequently overlooked. Both patients had been examined with the cystoscope before consulting me, but the cause of the most striking symptom, hematuria, had not been discovered. Doubtless this lesion was not recognized because of its location in the posterior vesical wall, a region that is frequently neglected or poorly examined in a routine inspection of the bladder.
The first case that I wish to report was interesting because of the sudden onset of the hematuria and the alarming amount of blood that was evacuated with each urination.
—Mrs. M. L. consulted me on July 3, 1911, because of frequency of urination, and because of the large amount of blood voided in
BUERGER L. ULCER OF THE BLADDER. JAMA. 1913;60(6):419–421. doi:10.1001/jama.1913.04340060011005
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