At the International Medical Congress in Rome in 1894 Dr. V. Gilbert stated that since 1891 he had treated tuberculous pleurisy with effusion by the subcutaneous injection of a small amount of the fluid withdrawn from the pleural cavity with an aspirating syringe. He found that within a few days after this injection, which he called "autoserotherapy," the serofibrinous exudate in the pleura disappears and the patient recovers. This method of treatment has been rather slow in gaining recognition, and was almost forgotten. During recent years, however, there have been reports from various clinics in Europe tending to show that there is great value in autoserotherapy, and its general adoption by the profession has been strongly urged. The animal experiments recently performed by Georg Eisner1 Show quite conclusively that there is a scientific basis for this mode of treatment, and that in experimental pleurisy autoserotherapy is of great
FISHBERG M. AUTOSEROTHERAPY IN SEROFIBRINOUS PLEURISY. JAMA. 1913;60(13):962–965. doi:10.1001/jama.1913.04340130010004
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