Assuming that the cause of arthritis deformans is a bacterial infection, cases of chronic infective deforming arthritis, or "chronic infectious arthritis," and arthritis deformans must be classed as the same disease etiologically. This assumption has been made by several, and a few physicians, on the basis of this assumption, have treated cases of arthritis deformans with streptococcus vaccines (Smith,1 Ball,2 Horder3). Horder and Smith have given good reasons for considering a particular vaccine specific for the disease.
An article by Skinner,4 in 1910, describing the results of 160 cases of arthritis deformans, claims much for the usual methods of treatment thoroughly carried out. He reports 25 per cent, apparently cured; 65 per cent. benefited in varying degrees, and 10 per cent, apparently uninfluenced. The 10 per cent, of uninfluenced cases is the class that specific therapy is supposed, by those who employ specific treatment for infective
HASTINGS TW. COMPLEMENT-FIXATION TESTS FOR STREPTOCOCCUS, GONOCOCCUS AND OTHER BACTERIA IN INFECTIVE DEFORMING ARTHRITIS AND ARTHRITIS DEFORMANS. JAMA. 1913;60(16):1208–1209. doi:10.1001/jama.1913.04340160010004
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