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May 3, 1913


Author Affiliations


JAMA. 1913;60(18):1358-1359. doi:10.1001/jama.1913.04340180020009

In June, 1907, I reported1 "A Case of Benign Melanosis" before the Section on Surgery of the American Medical Association at Atlantic City. Briefly:

A laparotomy in 1892 exposed a right ovarian cyst, black in color, and multiple small nodules studding the peritoneum. The operation was abandoned, a diagnosis of melanosarcoma made and several of the small nodules were removed. These nodules proved to be not melanosarcoma, but cysts containing very dark material which showed no cells capable of taking a stain. During convalescence the patient's urine, milk and sweat were deeply pigmented, but she made a good recovery. In 1895, the patient passed through a normal confinement and was delivered of a healthy child. At this time the milk and urine again became black, the condition lasting only a few days.

In view of the extreme rarity of this condition the subsequent history is of great interest: