From time to time injections of salvarsan in an oily medium have been recommended by various men, notably by Levy-Bing and Lafay,1 Kromayer,2 Pollitzer3 and Hazen.4 All of these men have, I believe, given up this method of administration in favor of the intravenous route, but without publishing their reasons for so doing. In view of the fact that a number of our best drug houses are now marketing preparations of salvarsan in oil, it seems wise to state my experience with this form of injection.
Up to the present time I have given fifty-eight of these injections to forty-four individuals. Fifty-two of the injections were of salvarsal. and six of the neosalvarsan. In general the effects on the lesions and on the Wassermann reaction were excellent. In the majority of instances the immediate results, so far as pain and disability are concerned, have also been
HAZEN HH. OILY INJECTIONS OF SALVARSAN—A WARNING. JAMA. 1913;60(21):1618. doi:10.1001/jama.1913.04340210028012
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