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To the Editor
—In The Journal for March 29, 1913, appears an editorial on "The Rattlesnake-Venom Treatment of Epilepsy," which, although chiefly aimed at another worker on this subject, is, in many instances, so manifestly unfair that I, who am wholly responsible for the origination of this method of treatment, cannot allow it to stand without a protest.In the first place, you seem to think that the essential feature in the setting aside of the epileptic seizures by crotalin resides in the injurious shocks and "severe reactions" which are incidental to its injection. Nothing could be farther from the truth. It is a fact that when the drug was first injected it was given in larger doses than have since been shown to be necessary to produce the desired results; but that it is absolutely indispensable to call forth a profound local or general reaction is not true, and
Mays TJ. The Rattlesnake-Venom Treatment of Epilepsy. JAMA. 1913;60(23):1811–1812. doi:10.1001/jama.1913.04340230057031
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