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Article
June 14, 1913

INTRAVENOUS INJECTIONS OF VARIOUS SUBSTANCES IN ANIMAL CANCER

Author Affiliations

ST. LOUIS

From the Department of Pathology of the Barnard Free Skin and Cancer Hospital.

JAMA. 1913;60(24):1857-1858. doi:10.1001/jama.1913.04340240013007

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Abstract

In continuation of our former work, we carried out a study of the action of two classes of substances on carcinoma in mice. First, we investigated the action of some inorganic substances; and, secondly, of various albuminous substances and also of a carbohydrate and a lipoid. We wish to give here briefly the result of our investigations.

Colloidal copper and colloidal platinum acted in a similar manner; both inhibited the growth of tumors during the time of injection. Colloidal sulphur, if active at all, is certainly not more active than either colloidal copper or platinum. On the other hand, easily ionized salts of copper and of lanthanum are without effect on cancer. Combinations of copper with proteid substances are active.

We also tested one organic substance which, according to Morgenroth, is very active in preventing pneumococcus infection, namely, ethylhydrocuprein. We found it without effect on cancer. Of the more complex

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