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To the Editor:
—In The Journal, May 17, 1913, p. 1533, Dr. H. G. Wetherill of Denver reports a successful case of bone-grafting without periosteum.In a report of our experimental bone and periosteal transplanting at the Texas State Medical Association the early part of this month, Dr. C. P. Brown and I were able to show conclusively that the periosteum had nothing to do with regeneration of the bone, and advocated at that time not only removing the periosteum from the transplant before it was removed from the tibia, but also taking off the superficial layer of the bone just beneath the periosteum and roughening the transplant with the chisel, in order to increase the osteoblastic-producing surface.In our last patient, operated on April 19, we not only removed the periosteum from the transplant, but also traumatized the surface formerly covered by periosteum. As the osteoblasts do not penetrate the
Brown WL. Bone-Grafting without Periosteum. JAMA. 1913;60(24):1900–1901. doi:10.1001/jama.1913.04340240060027
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