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Article
July 5, 1913

PURPURA, URTICARIA AND ANGIONEUROTIC EDEMA OF THE HANDS AND FEET IN A NURSING BABY

JAMA. 1913;61(1):18-19. doi:10.1001/jama.1913.04350010020008
Abstract

I wish to report a rare type of purpura and urticaria associated with angioneurotic edema of the hands and feet and other regions.

The patient was a boy, aged 6 months, strong and fat, nursed by a healthy mother.

First day:  On December 14 a dark, brawny swelling appeared, first in the left foot and then in the right foot. The child seemed ill and cried from pain in his feet. A few hours later a dark red edema involved the scrotum, and an erythema developed on the thighs and buttocks. The baby was given two doses of castor oil, 15 c.c. each, also an enema which caused a normal stool.

Second day:  In addition to the edema of the feet and genitals both eyes were closed by an effusion into the lids. The child was in continual misery from the tender ankles and refused to nurse. Fifteen c.c. of

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