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Article
August 2, 1913

DIURETICS IN CARDIAC DISEASE: A GENERAL REVIEW

JAMA. 1913;61(5):340-344. doi:10.1001/jama.1913.04350050022009
Abstract

In considering the subject of diuretics in cardiac disease it is essential that we frame in our minds some tentative idea of the forms of cardiac disease in which it is desirable to resort to diuretics at all; secondly, that we form a clear idea of the manner in which the lesion of the heart affects the action of the kidney; and thirdly, that we consider the mode of action by virtue of which the particular diuretic drugs under consideration may be expected to remedy these disturbed conditions.

With full realization that I am making rough and arbitrary divisions, I may say that one might consider the advisability of resorting to diuretic measures in five forms of disease of the circulation: (1) infective endocarditis; (2) arteriosclerosis with periodic attacks of the various disturbances associated with localized arteriosclerosis, vertigo, headaches, transitory cardiac asthma or pulmonary edema, angina pectoris and vasomotor crises;

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