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Article
August 2, 1913

THE SIGNIFICANCE OF PLASMA CELLS IN THE TONSIL: A PRELIMINARY REPORT

JAMA. 1913;61(5):345-347. doi:10.1001/jama.1913.04350050027010
Abstract

In an article published last year,1 I emphasized the significance of what I called the hyperfunctionating tonsil in childhood. I there said:

"Mere fluctuation in size of a tonsil in a child ought not to be regarded as a sign of local disease and an indication for enucleation. Many children are constitutionally subject to such fluctuations and the treatment is general more than local." "It is common knowledge that in systemic diseases we have such enlargements and few of us are disposed to argue that these are a sign of focal disease. I would rather regard them as indications of functional activity." Speaking with reference to the region where the respiratory and alimentary tracts meet, I said: "As knowledge advances there is constantly impressed on us the important and unexpected relation of this region to disease. We err if we forget that here as elsewhere the essential resisting power

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