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Article
August 2, 1913

THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

JAMA. 1913;61(5):348-351. doi:10.1001/jama.1913.04350050030011
Abstract

THE CHANGING THEORIES OF DIABETES  The treatment of diabetes in recent years has been kept in close harmony with the prevailing theory of the immediate cause of its symptoms. It is agreed among all who have first-hand knowledge of the disease that the glycosuria is due to an overloading of the blood with sugar. As we have previously pointed out,1 the hyperglycemia is the uppermost fact which establishes the abnormal metabolism of diabetes. How the overloading of the organism with sugar comes about is, of course, a fundamental question. The practice in the direction of restricting the intake of carbohydrate has been based on the belief in the inability of the diabetic organism to use sugar in the normal manner; and there is no dearth of evidence to support the current assumption. Of late, however, another theory has begun to be spread about in this country; and since it

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