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In the spring of 1912 there occurred in my clinic at Wills' Hospital that curious coincidence occasionally noticed by every clinician, of seeing within a short period of time several cases of an uncommon affection. In this instance it was hydrophthalmos, and the coincidence was even more striking in that all three cases were in negroes.
As I could recall seeing but six cases of this disease and as four of these occurred in negroes, in two of which there was a strong suspicion of hereditary syphilis, it seemed as if this might be more than an accidental association. With this thought in mind and with the recollection of an unfortunate outcome to the operative treatment by different methods and by two different operators of the eyes of a baby presenting a marked degree of hydrophthalmos, it was believed that it would be of value to collate the opinion of
ZENTMAYER W. HYDROPHTHALMOS: WITH A HISTOLOGIC REPORT OF TWO CASES, ONE OF WHICH PRESENTED A CONGENITAL COLOBOMA. JAMA. 1913;61(13_part_2):1103–1110. doi:10.1001/jama.1913.04350140019005
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