The purpose of this paper is, first, briefly to discuss the present status of the question of anesthetics, secondly, to contribute data from the Mayo Clinic, and, lastly, to present some preliminary observations on an experimental work which is to be continued at length.
A stimulus has recently been applied to the question ofanesthesia, which has resulted in a wide-spread interest and in laudable endeavors toward advancement. New anesthetics and various combinations have been employed, apparatus aiming at accuracy has been designed and different routes of administration have been practiced. Commendable and seemingly progressive as are all these efforts, still does not their multiplicity itself emphasize the general state of inefficiency that exists?
To enumerate and describe the several anesthetics, devices and methods which have been advanced would be an unnecessary repetition, since their details are already known, or at least are easily available in the literature. Each has enthusiastic
McGRATH BF. A DISCUSSION OF VARIOUS ANESTHETICS AND METHODS: EXPERIMENTAL OBSERVATIONS. JAMA. 1913;61(17):1516–1521. doi:10.1001/jama.1913.04350180016006
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