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To the Editor:
—The paper of Noguchi on the "Cultivation of the Parasite of Rabies (Jour. Exper. Med., 1913, xviii, 314; abstr., The Journal A. M. A., Sept. 20, 1913, p. 993), has a special interest for 993), student of hydrophobia. Is the cause indeed a parasite, or is it, as Ferran supposed, a ferment? Are the Negri bodies parasites, or do they simply enclose an invisible germ, the true parasite, of which the Negri corpuscle is the outward and visible expression? This view, which is probably at present the most illuminating, is represented by two admired and popular authors, Babes, who regards the Negri inclusions as the reaction of the cell to the parasite, and Prowazek, who classifies the parasite among the Chlamydozoa. Both the parasite and the Negri bodies have been connected by some writers with the Protozoa; but in view of the fact that the Negri corpuscles
Bartholow P. The Parasite of Rabies. JAMA. 1913;61(17):1555–1556. doi:10.1001/jama.1913.04350180055021
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