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November 22, 1913


JAMA. 1913;61(21):1869-1870. doi:10.1001/jama.1913.04350220013004

The first experimental work on transplantation of the testicle was done by Berthold1 in 1849. He used completely castrated roosters and transplanted the testicle into the abdominal cavity. The transplanted testicle grew, maintained its peculiar character as a sexual organ, and the male habits of the chicken continued.

Other investigators have confirmed this result in chickens. In frogs, Herlitzka2 transplanted testicles into the peritoneal cavity, and found that they degenerated and became absorbed.

Meyns3 worked with frogs and implanted parts of the testicle into the dorsal lymph-vessel of the frog and found that these transplants grew and developed new mature spermatozoa.

The size of the transplanted organ has a great deal to do with the success or failure of the operation. If the testicle is transplanted in toto, it is almost certain to necrose. If it is cut into thin slices from 1 to 2 mm. in