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Article
December 6, 1913

The Regeneration of the Blood After Splenectomy

Author Affiliations

Philadelphia.

JAMA. 1913;61(23):2087-2088. doi:10.1001/jama.1913.04350240061029

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Abstract

To the Editor:  —The editorial on this subject (The Journal, Nov. 15, 1913, p. 1816) gives such an incorrect idea of the present state of our knowledge concerning this subject that I feel compelled to call attention to certain discrepancies in the data on which the editorial is based. An extensive study of the changes in the blood following splenectomy in the normal dog, carried out under my direction during the past two years (Pearce, R. M.: The Relation of the Spleen to Blood Destruction and Regeneration and to Hemolytic Jaundice, Papers I-VII, Jour. Exper. Med., 1912, xvi, 363, 375, 758, 709, 780; 1913, xviii, 487, 494; an eighth paper is now in press [Jour. Exper. Med., December, 1913]) has demonstrated conclusively that the spleenless animal always develops an anemia which is progressive for several weeks, usually reaching its period of greatest severity after from three to six weeks and

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