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Article
December 13, 1913

A THEORY OF THE CAUSE OF ECTOPIC PREGNANCY

Author Affiliations

ALBANY, N. Y.

JAMA. 1913;61(24):2130-2136. doi:10.1001/jama.1913.04350250016005
Abstract

Various speculations have seemed to explain the cause of ectopic pregnancy because, as we shall see later, they contain an element of truth so far as based on secondary causes present in only a few cases. Webster1 was the first to formulate a working hypothesis comprehensive enough to embrace most of the observed phenomena and sufficiently fundamental to be a means to furthering our knowledge of the cause, when he definitely stated that the ovum always embeds in Müllerian tissue. At the time he formulated this hypothesis he had in mind that ectopic pregnancy always originates as tubal pregnancy; that is, the ovum embeds in the tube and not in the ovary (ovarian pregnancy) or in the peritoneum (abdominal pregnancy); but later, after undoubted cases of ovarian pregnancy were observed, he explained them as due to the extension of Müllerian tissue into the ovary. This hypothesis of Webster's leaves

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